Navigated advanced rTMS complete solution
This complete package includes everything you need for precise and efficient navigated rTMS treatments of many disorders. The solution includes a reliable and powerful rTMS device in combination with the Neural Navigator Essentials system which uses unique electromagnetic tracking in a fully integrated setup for clinical or research use. Furthermore, a comfortable reclining treatment chair and different types of compatible rTMS coils are available. All devices in this solution are CE certified for clinical use in the EU and FDA cleared for clinical use in the USA.
Neurosoft advanced therapeutic rTMS
20 Hz stimulation with 100% intensity
Due to the additional power supply unit, the advanced therapeutic system provides the possibility to increase four times (up to 20 Hz) the maximal effective stimulation frequency (the frequency when each stimulus in series has 100% intensity of motor threshold).
Theta burst stimulation and the 3-minute depression treatment protocol
This powerful machine allows new patterned rTMS protocols such as Theta Burst Stimulation (TBS), intermittent TBS (iTBS) and continues TBS (cTBS) with frequencies up to 100Hz, without overheating due to superior cooling technology. In accordance with the clinical tests performed by leading research hospitals in Canada, in patients with treatment-resistant depression, iTBS was non-inferior to 10 Hz rTMS for the treatment of depression (Blumberger et al 2018). Both treatments had low numbers of dropouts and similar side-effects, safety, and tolerability profiles. With iTBS, the number of patients treated per day with current rTMS devices can be increased several times without compromising clinical effectiveness.
In summary, the 3-minute treatment is as safe and effective for the depression treatment as the conventional rTMS sessions that take more than 20 minutes.
Number of pulses & peak magnetic field
The unit allows continuous operation up to 10.000 pulses without overheating due to the cooling unit and the cooled coils. The peak magnetic field is 4 T, one of the highest values in the industry which supports the therapeutic transcranial magnetic stimulation in most complicated treatments of patients with a very low level of cortex excitability.
Neuro-MS.NET software
This set includes the special Neuro-MS.NET software that allows to customize or to create any stimulation template. This software keeps track of patient databases, detects motor response threshold and controls the stimulation sessions.
The Neural Navigator
Features & performance
- Precision: The Neural Navigator can target brain areas indicated on an individual MRI scan with a precision of at least 4 mm (Neggers et al, 2004).
- Tracking technology: electromagnetic tracking using highly robust DC pulsed EM tracking (often used in neurosurgical neuronavigation). The precision of the tracking is at least 1mm.
- MRI scans needed: straightforward T1 weighted MRI scan at around 1mm cubic resolution.
- Formats supported: DICOM import/export, Nifti import/export. fMRI and DTI results from SPM/FSL/AFNI are readable.
- Built in robust semi-automatic MRI scan segmentation.
- Supports fMRI activation overlays and targeting.
- Actual 3D coil models for most Neurosoft coils built into the software.
Delivery set of complete system
- Neuro-MS/X main stimulation unit
- Neuro-MS/X cooling unit
- Neuro-MS/X extra power supply unit
- Angulated figure-of-eight cooled coil 100 mm AFEC-02-100-C
- Flexible arm for coil positioning
- Special trolley with 4 shelves, arm for EM transmitter and arm for 2nd screen, side mount for tracking system and coil arm.
- Coil holder , trolley or wall mounted
- The Neural Navigator software suite "Essentials"
- The BrainTRAK neuronavigation position tracker with 4 tracking sensors and magnetic field transmitter.
- Plastic hand-held pointer for measuring facial landmarks and a remote control for navigation.
- A sturdy suitcase with compartments fitting all navigator components, allowing easy and safe transportation and storage
- A navigation compatible reclining comfortable TMS treatment chair.
- Technical and user manuals
- NeuroMS software to control TMS equipment from PC
- All required cabling
Regulatory
- The Neural Navigator and Neuro MS/X rTMS system are CE certified as a class IIa medical device in the European Union and FDA cleared in the USA, Furthermore, all equipment is InMetro and ANVISA certified in Brazil, and TGA certified in Australia. In these regions the entire setup can be used for clinical purposes.
- The setup as an electrical medical device is compliant with IEC 606011 3rd edition (Electrical Safety) and IEC 60601-1-2 3rd edition (electromagnetic compatibility) as well as RoHS and WEEE.
Reproducible coil placement using MNI
The neural navigator supports accurate reproduction of TMS coil positions using an MNI template. Similar to the standard navigation procedure, facial landmarks of the MNI template are captured on the participant's head. Next, the neural navigator adjusts the MNI template based on the geometry of the participant's head. MNI targets, …
rTMS treatment of neuropathic pain
Neuropathic pain is characterized by a distinct set of symptoms, such as a burning sensation and pain resulting from non-painful stimulations. Fibromyalgia, orofacial pain, and phantom pain are different types of neuropathic pain. Neuropathic pain is caused by damage to, or a disease of the somatosensory system and it’s estimated …
rTMS treatment in stroke rehabilitation
Stroke patients are often left with impairment of the upper limbs, even after intensive rehabilitation of upper limb function. The impairment of the upper limb is associated with disrupted activity within the brain's motor network. The disrupted activity is characterized by reduced activity in the affected motor cortex, which causes …
EM versus optical tracking in neuronavigation
During neuronavigation, the 3D position and angle of the TMS coil, a digitizing stylus and the head of the patient typically must be known at all times. Position tracking can be performed either using optical tracking with large cameras, or electromagnetic (EM) tracking based on a DC pulsed magnetic field …
Treatment of Major Depressive Disorder
MDD, also referred to as clinical depression, is a significant medical condition that can affect many areas of life. MDD is one of the most common mental disorders, 1 out of 6 adults experiences depression. Standard treatment of MDD is medication and psychotherapy. However, about a third of patients with …
Transcranial Magnetic Stimulation in OCD
Obsessive-compulsive disorder (OCD) is a disorder characterized by uncontrollable, recurring thoughts and behaviors. About 2% to 3% of people experience OCD, yet standard treatment such as medicine or exposure therapy achieves (partial) response in only 40% - 60% of the patients. In May 2019 a new treatment was approved by …
Theta burst stimulation (TBS)
rTMS treatment protocols continue to be investigated and improved. New patterned rTMS protocols, where short high frequency trains of TMS pulses are are interleaved with really short breaks, are referred to as Theta Burst Stimulation (TBS), intermittent TBS (iTBS) and continues TBS (cTBS) with frequencies up to 100Hz for the …
